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Electrochemical Behavior and Determination of Cilostazol in Pure, Urine and in Pharmaceutical Formulations
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نویسنده
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wassel A. Anwar ,Amin S. A. ,Dessouki A. H. ,Hendawy M. A.
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منبع
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analytical and bioanalytical electrochemistry - 2012 - دوره : 4 - شماره : 2 - صفحه:197 -211
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چکیده
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The adsorptive and electrochemical oxidation behavior of cilostazol has beenstudied at cpe and gce in britton - robinson (br) (ph 2.0 to 12.0). the anodic oxidation at663 and 682 mv for cpe and gce respectively. differential pulse voltammetry was used todetermine cilostazol in the pure and in pharmaceutical formulations. the linear calibrationwas obtained from: 4.0×10-7–6.40×10-6 m and 5×10-7–8.7×10-6 m for carbon past and glassycarbon electrode. the percentage recoveries were found in the ranges: 99.50-100.80%, 99.20-100.10% at carbon past and glassy carbon electrodes, respectively. the rsd for fivemeasurements were found in the ranges: 0.403-0.742% and 0.657-0.84 %,. the method wasapplied to determine cilostazol has in dilute urine sample and dosage forms and comparedwith official methods.
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کلیدواژه
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Carbon Past Electrode ,Glassy Carbon Electrode ,Differential Pulse Cyclic ,Cilostazol Assay ,Dosage Forms
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آدرس
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National Organization for Drug Control and Research, (NODCAR) P.O. Box 29, Cairo, Egypt, Egypt, Benha University, Department of Chemistry, Faculty of Science, Benha University, Benha, Egypt, Egypt, Benha University, Department of Chemistry, Faculty of Science, Benha University, Benha, Egypt, Egypt, National Organization for Drug Control and Research, (NODCAR) P.O. Box 29, Cairo, Egypt, Egypt
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Authors
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