Electrochemically Different Behaviors of Cytochrome c in the Presence of Organic Phosphates

The electrochemical effects of adenosine triphosphate (atp), guanosine 3',5'-tetraphosphate (gtp), guanosine diphosphate (gdp) and guanosine monophosphate(gmp), on the cytochrome c, were investigated with the iodide modified silverelectrode in 0.01 m kno3 at ph 7.0. anodic and cathodic peaks were observed at 550and 94 mv vs. ag/agcl, and the formal potential was calculated to be 322 mv vs.ag/agcl. the effects of atp, gtp, gdp and gmp concentrations were determined onthe anaerobic redox reaction. atp led to a positive shift in the anodic and cathodicpeaks of cytochrome c (cyt c) to 599 and 141 mv, respectively. these shifts caused afacilitated-reduction reaction whilst the oxidation one became harder in the presence ofatp. gtp caused a positive shift in the cathodic peak up to 152 mv and a negativeshift in the anodic peak to 495 mv, resulting in facilitated oxidation and reductionreactions of cyt c. gdp decreased the anodic and cathodic peak currents withoutchanging their potentials, whilst gmp did not affect the cathodic and anodic peaks ofcyt c, indicating the lack of affinity of cyt c for this material.