Electrochemical Approach for Determination of Tertahydrozoline HCl using Gold Nanoparticles Electrode

The electrochemical behavior of tetrahydrozoline (thz) was explored by cyclic voltammetry and differential pulse voltammetry. a well-defined peak at 915 mv using gold nanomodified electrode (aunpts/cp) in presence of sodium dodecyl sulphate (sds) was detected. different buffers, ph and scan rates on oxidation peak current were studied. linear calibration curve was achieved in the range of 1.99×10^−5 to 7.79×10^-5 m with a limit of detection (lod) 5.54×10^-6 m and limit of quantification (loq) 1.69×10^−5 m, respectively. the suggested method was successfully utilized to the eye drops dosage form and urine sample with percentage recovery, 98.86%±0.77, and 101.13±0.62, respectively.