Electrochemical Determination of Sulfapyridine using a New Approach of Modified Electrode based on Amplification with Room Temperature Ionic Liquid and ZnO Nanoparticle

An electroanalytical sensor amplified with zno nanoparticle (zno nps) and 1- butyl-2,3-dimethylimidazolium hexafluorophosphate (1b23dipf6) was fabricated as new analytical approach for determination of sulfapyridine in different real samples. the zno nps was synthesized by a simple precipitation method with low calcination temperature (⁓ 300 °c) and characterized by xrd and fesem methods and results confirm a particle size ⁓45.2 nm for zno nps. in addition, the two-fold amplification of paste electrode (pe) with zno nps and 1b23dibr (pe-zno nps-1b23dipf6) created a new tool for determination of sulfapyridine in the concentration range of 0.09-400 µm with detection limit 30.1 nm. on the other hand, the pe-zno nps-1b23dipf6 showed recovery data between 99.4%-104.1% for determination of sulfapyridine in some different real samples such as urine and tablet.