Tetrafurfurylamine Anchored N4-Macrocycle as Potential Catalyst for Electrochemical Redox Reactions of Biomolecules

In this study novel tetra furfurylamide substituted metal phthalocyanine (m=co, cu, ni & zn) were synthesized and characterized by elemental analysis, ultra-violet, fourier transfer infrared spectroscopy, mass spectroscopy and powder x-ray diffraction analysis. the cobalt (ii) tetra furfurylamide phthalocyanine (cotfurnh_2pc) tailored gce was constructed by drop covering technique. the fabricated electrode was subjected for electrochemical investigation of oxidizable species such as dopamine (da), uric acid (ua) and reducible moiety like dimetridazole (dmz). it was noticed that cotfurnh_2pc/gce exhibits admirable electrochemical performance for dopamine, uric acid oxidation and dimetridazole reduction in pbs ph 7.0. the sensor exhibits sensitivity for da (cv 0.179, dpv 0.333, ca 0.486 μa μm^-1cm^-2), for ua (cv 0.517, dpv 0.374, ca 0.129 μa μm^-1cm^-2), for dmz is (cv - 8.55, dpv -13.73, ca -0.393 μa μm^-1cm^-2) respectively (s/n=3). biomolecules present in same solution can be sensed by constructed electrode with peaks resolution of 348 millivolts and 318 millivolts for dopamine-dimetridazole and dimetridazole-uric acid respectively. the cotfurnh_2pc fabricated electrode has various useful properties like high repeatability, quick response and steadiness. further dpv and chronoamperometric of titled compound has been studied.