Effect of soy isoflavones on acne vulgaris

Objective to demonstrate the effect of soy isoflavones on acne vulgaris (av) lesions in female patients. methods in this randomized pretest-posttest control group design,25 patients were randomized into 5 groups: isoflavones 40 mg,80 mg,120 mg,160 mg and placebo,and treated for 4 weeks. results the mean total av lesions before treatment among the five groups was similar (p=0.259),whereas after treatment significant difference was observed (p=0.001). intergroup comparison revealed that decrease in the mean total av lesion count before and after treatment was significant in isoflavone 160 mg group (p<0.05 ),while in the placebo,40 mg,80 mg,120 mg groups it was insignificant (p>0.05 ). conclusion soy isoflavones supplementation 160 mg/day can lower total av lesion.