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Leprosy: Type 1 reaction precipitated by doxorubicin and cisplatin
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نویسنده
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das s. ,das s. ,ghoshal l. ,malo s.
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منبع
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journal of pakistan association of dermatologists - 2015 - دوره : 25 - شماره : 1 - صفحه:55 -57
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چکیده
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Type 1 reaction (t1r) in leprosy is common and characterized by increased inflammation in skin lesions or nerve. besides antileprotic therapy,t1rs are associated with intercurrent infection,pregnancy and drugs. also,t1rs may be a presenting feature of leprosy. we report a case of t1r in leprosy presenting as drug reaction during cancer chemotherapy with doxorubicin and cisplatin. we propose to explain this unusual occurrence by highlighting the increased production and expression of tnf-a by these drugs. thus,physicians using these drugs should keep this unusual adverse effect in mind.
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کلیدواژه
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Anticancer chemotherapy; Tumor necrosis factor-α; Type 1 leprosy reaction
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آدرس
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department of dermatology,nil ratan sircar medical college and ohospital, India, department of dermatology,nil ratan sircar medical college and ohospital, India, department of dermatology,nil ratan sircar medical college and ohospital, India, department of dermatology,nil ratan sircar medical college and ohospital, India
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Authors
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