A case of refractory chronic spontaneous urticaria treated with omalizumab

Chronic spontaneous urticaria (csu) is a chronic and refractory dermatosis. omalizumab is a relatively new addition to csu therapeutic armamentarium. we present a 52-year-old male having symptoms of chronic spontaneous urticaria (csu) of moderate severity for last 15 years. he was on regular h1 antagonist and mast cell stabilizers was started with 300 mg omalizumab on monthly basis,urticaria activity score started improving after second month. patient is still using h1 antagonist but not regularly but with a liberal lifestyle as compared to previously.