Aplasia cutis congenita in two brothers - a rare occurrence

Aplasia cutis congenita (acc) is characterized by the absence of a portion of skin in a localized or widespread area at birth. it is a rare disorder with a complicated pattern of inheritance. no unifying theory can account for all lesions of acc. apart from the isolated finding of aplasia cutis; several reports have associated it with a large number of developmental anomalies. therefore, a complete physical examination should be performed to search for associated physical anomalies or recognizable malformation syndromes. we document two brothers aged, 6 years and i year, who presented with aplasia cutis congenita at almost the same location on scalp.