total flavonoids contents and anti bacterial activity of the extracts of two labiateae species: nepeta menthoides and thymus trautvetteri

Total flavonoids contents and antibacterial activity of the extracts from the aerial parts of two labiateae species, nepeta menthoides boiss. buhse and thymus trautvetteri klokov desj.-shost. were determined. quantitative determination of flavonoid contents was calculated in terms of quercetin equivalent in various extracts (50% methanol, chloroform and distilled water) by alcl3 colorimetric method. it was found that total flavonoids contents of n. menthoides extracts in different solvents were (2.308%, 0.884% and 0.710%) mg/g and (2.076%, 1.468% and 1.412%) mg/g for t. trautvetteri  respectively.antibacterial activity of the extracts was also determined against 6 gr (+/-) bacteria by disc diffusion method. the results showed that 50% methanol extracts of two species displayed better inhibitor activity against the tested bacteria. the bacteria stapylococcus epidermidis, staphylococcus saprophyticus and staphylococcus aureus  were sensitive against 50% methanol extract of n. menthoides even more than the standard antibiotics (10μg). therefore a good correlation between total flavonoids contents and antibacterial activity of the studied extracts is demonstrated.