Effect of Solvent Type on Rosmarinic Acid, Total Phenol, Flavonoids, andAntioxidant Activity of Nepeta asterotricha Rech. f: An Endemic Plant from Iran

The current study aims to investigate the effect of solvent variety on some phytochemical factors of nepeta asterotricharech. f.: as an endemic plant from iran. it is suspected that quantity and quality of chemical compounds would be affectedby solvent type. for this purpose, aqueous, hydro-alcohol (50/50 ethanol/water), and methanol were used as solvents. thestudied factors were total phenol, flavonoid, antioxidant activity, and rosmarinic acid that were measured by folin-ciocalteu, colorimetric, frap, and hplc methods, respectively. the outcomes showed hydro-alcohol extraction couldsignificantly isolate phenol compounds (156.84 mg gae/g dw) with considerable antioxidant properties (318.55 mgaa/g dw). however, methanol was more effective to extract total flavonoid content (101.34 mg re/g dw) androsmarinic acid (140.39% dw). in addition, more study should be done to investigate the importance of each compoundsfor both medicinal and industrial uses.