Evaluation of Serum 25-Hydroxy Vitamin D Levels in Children with Acute Bronchiolitis

Background: according to some reports, 25-hydroxy vitamin d (25 (oh) d) deficiency leads to respiratory diseases. given the high prevalence of acute bronchiolitis in young infants, the assessment of 25 (oh) d status is very important for this disease. objectives: this study was conducted to determine the relationship between the serum levels of 25 (oh) d and acute bronchiolitis in young infants. methods: in the present study, 57 patients with acute bronchiolitis (case control) were compared with 57 healthy children (control group) in terms of 25 (oh) d serum levels. the serum levels of 25 (oh) d were measured using the elisa method. the results were analyzed and compared between the two groups. results: the mean and standard deviation of 25 (oh) d serum levels were 26  9.5 and 23.3  8.3 ng/ml in the case and control groups, respectively. no significant difference was observed between the two groups in terms of 25 (oh) d serum levels (p = 0.11). conclusions: this study showed that there is no significant difference between children with acute bronchiolitis and normal children in terms of serum 25 (oh)dlevels. it therefore seems that 25 (oh) d does not play any role in the pathogenesis of acute bronchiolitis. further studies in this area are recommended.