analysis of clinical and radiologic parameters in children diagnosed with covid-19 infection at admission and discharge

Background: recognizing risk factors for poor prognosis among covid-19 patients is crucial, especially given the absence of standardized treatments and medications. objectives: in the present study, our aim was to survey changes in clinical parameters in children diagnosed with covid-19 infection from admission to discharge. methods: the present retrospective cross-sectional study focused on children with covid-19 infection. all demographic data and clinical information of patients were extracted upon admission and at discharge from the hospital. data analysis utilized the mann-whitney u test and fisher exact test. multivariable regression modeling was employed to identify factors predicting the probability and duration of hospitalization in icus for children with covid-19. results: elevated levels of esr, crp, creatinine, and ferritin were found in 51.7%, 67.4%, 69.3%, and 53.6% of patients upon admission. moreover, 98.2% and 38.3% of patients had high levels of alp and ast. platelet (plt) and neutrophil levels were higher at discharge compared to admission (p < 0.001), while creatinine levels were lower at admission than at discharge (p < 0.001). patients admitted to icus exhibited significantly higher levels of pulse rate (p < 0.001), respiratory rate (p < 0.001), mean corpuscular volume (mcv) (p = 0.01), red cell distribution width (rdw) (p = 0.002), prothrombin time (pt) (p = 0.006), and esr (p = 0.04). conclusions: pulse rate, respiratory rate, mcv, rdw, pt, esr, and oxygen saturation (spo 2) percentage can be used to predict the severity of covid-19 disease. however, further studies are needed to determine the prognosis and severity of covid-19 infection in children.