is there a correlation between vitamin d levels and acute diarrhea in children?

Background: some studies have shown that low vitamin d is a risk factor for infectious diarrhea, but some have rejected it. objectives: considering the high prevalence of infectious diarrhea among children, the high prevalence of vitamin d deficiency, and the possible mutual effect of these two, the present study aimed to measure vitamin d in children with acute diarrhea. methods: this study enrolled 222 children aged 2 - 14 in healthy control and acute diarrhea groups. the 25-hydroxyvitamin d (25(oh)d) level was measured in all samples by the chemiluminescent immunoassays (clia) method. results: the mean age of the participants was 5 ± 2.7 years. patients with acute diarrhea had lower vitamin d than healthy controls (p = 0.04). the frequency of deficient and insufficient vitamin d levels was higher in the acute diarrhea group than in the healthy control group, but insignificantly (p = 0.146). conclusions: the present study revealed an association between insufficient vitamin d and acute diarrhea. hence, low vitamin d is a risk factor for acute diarrhea.