Histopathological study of primary bone tumours and tumour-like lesions in a medical teaching hospital

Objectives: histopathological study of bone tumours to determine the spectrum of bone tumours at a medical teaching hospital and to correlate it with demographic features like age,sex of patients and anatomical site of tumours. material and methods: a retrospective and prospective study of all histopathologically diagnosed bone tumours over a period of 10 years was done. patients were assessed by clinical examination,radiological investigations,histopathological examination and fine needle aspiration cytology (fnac) whenever available. results: a total of eighty-two cases of primary bone tumours were recorded,of which benign tumours were the most common 62 cases (75.61%) followed by malignant tumours with 13 cases (15.85%) and 7 cases (8.54%) of tumour-like lesions. fnac diagnosis was available in 26 cases (31.71%) with 68.96% benign tumours,17.24% malignant and 3.45% were tumour–like lesions. the concordance and discordance rate of histopathological diagnosis was 76.93% and 23.07% respectively. on histopathological diagnosis,the most common benign tumour was osteochondroma 34.15% followed by giant cell tumour 19.51%. osteosarcoma was commonest malignant tumour 8.54%. maximum number of bone tumours occurred in 11-20 years of age and the male to female ratio was 1.2:1. conclusions: bone tumours occurred predominantly in the second decade of life with a male preponderance. osteochondroma was the most common benign tumour followed by giant cell tumour and osteosarcoma was the most common malignant bone tumour. © journal of krishna institute of medical sciences university.