Alterations in some biochemical parameters and trace elements in asthmatic patients in Owerri

Background: asthma is a chronic disease characterized by recurrent cough and wheeze. aim and objectives: to determine the level of some biochemical parameters and trace elements in asthmatic patients attending general hospital owerri. material and methods: thirty six confirmed asthmatic patients and thirty six apparently healthy subjects (control) between the age of 10 to 30 years were selected in this study. serum trace elements: zinc and copper,malondialdehyde,vitamin c,vitamin e,immunoglobulin a and immunoglobulin e were estimated using standard methods. results: there serum levels of copper,ige,iga and mda were significantly increased in asthmatic patients when compared to control (p<0.05). while the serum levels of zinc,vitamin c and vitamin e were significantly decreased in asthmatic patients when compared with the control (p< 0.05). conclusion: these observations probably indicated that asthmatic patients could be prone to the oxidative stress. also,foods or diets containing antioxidants could be beneficial to asthmatic patients. © journal of krishna institute of medical sciences university.