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Phytochemical investigation and antimicrobial activity of an endophytic fungus Phoma sp.
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نویسنده
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hussain h. ,john m. ,al-harrasi a. ,shah a. ,hassan z. ,abbas g. ,rana u.a. ,green i.r. ,schulz b. ,krohn k.
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منبع
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journal of king saud university - science - 2015 - دوره : 27 - شماره : 1 - صفحه:92 -95
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چکیده
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Phytochemical investigation of the endophytic fungi phoma sp. resulted in the isolation of sclerodin (1),8,9-dihydro-3,5,7-trihydroxy-1,8,8,9-tetramethyl-5-(2-oxopropyl)-4. h-phenaleno[1,2- b]furan-4,6(5. h)-dione (2),atrovenetinone (3),and sclerodione (4). preliminary studies showed that sclerodin (1) displayed moderate antialgal activity while 8,9-dihydro-3,5,7-trihydroxy-1,8,8,9-tetramethyl-5-(2-oxopropyl)-4. h-phenaleno[1,2- b]furan-4,6(5. h)-dione (2),atrovenetinone (3),and sclerodione (4) displayed moderate antifungal activity. furthermore 8,9-dihydro-3,5,7-trihydroxy-1,8,8,9-tetramethyl-5-(2-oxopropyl)-4. h-phenaleno[1,2- b]furan-4,6(5. h)-dione (2) and atrovenetinone (3) showed moderate antibacterial activity against bacillus megaterium and additionally atrovenetinone (3) showed good antibacterial activity towards eurotium repens. furthermore atrovenetinone (3) and sclerodione (4) displayed very strong antifungal activity towards ustilago violacea. © 2014 king saud university.
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کلیدواژه
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Antimicrobial activity; Endophytic fungi; Phoma sp.
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آدرس
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department of chemistry,university of paderborn,warburger strasse 100,paderborn,germany,uon chair of oman's medicinal plants and marine natural products,university of nizwa,po box 33,birkat al mauz, Oman, department of chemistry,university of paderborn,warburger strasse 100, Germany, uon chair of oman's medicinal plants and marine natural products,university of nizwa,po box 33,birkat al mauz, Oman, department of chemistry,quaid-i-azam university, Pakistan, uon chair of oman's medicinal plants and marine natural products,university of nizwa,po box 33,birkat al mauz, Oman, uon chair of oman's medicinal plants and marine natural products,university of nizwa,po box 33,birkat al mauz, Oman, deanship of scientific research,college of engineering,king saud university, Saudi Arabia, department of chemistry and polymer science,university of stellenbosch,p/bag x1, South Africa, institute of microbiology,university of braunschweig,spielmannstraße 7, Germany, department of chemistry,university of paderborn,warburger strasse 100, Germany
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Authors
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