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A Novel Synthesis of 2-(Alkylamino) and 2-(Arylamino)- 4(3H) Quinazolinones by Heterotrocyclization of 2-Aminobenzamide with Isothiocyanates (or Isocyanates) under Microwave Irradiation
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نویسنده
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Tavallaii Z ,Sabzevari O ,Bakavoli M ,Rahimizadeh M
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منبع
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scientia iranica - 2007 - دوره : 14 - شماره : 4 - صفحه:320 -322
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چکیده
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A convenient one-pot preparation of 2-(alkylamino) and 2-(arylamino)-4(3h) quinazolinones in high yields has been developed by microwave induced heterocyclization of 2-aminobenzamide with isothiocyanates (or isocyanates) in solvent-free conditions. in comparison, the reactions are faster under microwave irradiation and the yields are much higher than those by/of conventional heating (under reflux in toluene)
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آدرس
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ferdowsi university of mashhad, ایران, ferdowsi university of mashhad, ایران, ferdowsi university of mashhad, ایران, ferdowsi university of mashhad, ایران
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Authors
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