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a simple chaotic model for development of hiv virus
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نویسنده
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sprott j. c. ,jafari s. ,aram z. ,parastesh f. ,namazi h. ,jafari s. ,aram z. ,namazi h. ,sprott j. c. ,parastesh f.
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منبع
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scientia iranica - 2021 - دوره : 28 - شماره : 3-D - صفحه:1643 -1652
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چکیده
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Investigation into the spread of hiv virus as one of the fastest infectious viruses through human body is essential. mathematical modeling facilitates the processand evaluation of the experimental tests. it can also help predict the disease progress and provide a better understanding of the virus development. in this study, a new nonlinear di erential equation model was proposed to investigate the interaction be tween the hiv virus and body immune system. this ysiological-based model was capable of representing complex behaviors. the bifurcation analysis of some variations of activated healthy t cells was carried out. it was shown that the chaotic development of the virus was detected in a number of activated healthy t cells. this may explain why the virus develops di erently in di erent individuals or under di erent circumstances. the chaotic region contains some narrow periodic windows in which the chaotic mode suddenly ends at some critical points and the system exhibits a periodic behavior in a small range of active healthy t cells.this nding conrms the possibility of controllable development of the hiv virus, even when it is at a random-like phase. for further illustration, the state space of the system is represented.
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کلیدواژه
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hiv virus ,mathematical modeling ,nonlinear dynamics ,chaos ,bifurcation ,physiological-based model
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آدرس
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university of wisconsin-madison, department of physics, usa. university of wisconsin-madison, department of physics, usa, amirkabir university of technology, health technology research institute, department of biomedical engineering- department of biomedical engineering, iran. amirkabir university of technology, health technology research institute, department of biomedical engineering- department of biomedical engineering, iran, amirkabir university of technology, department of biomedical engineering, iran. amirkabir university of technology, department of biomedical engineering, iran, amirkabir university of technology, department of biomedical engineering, iran. amirkabir university of technology, department of biomedical engineering, iran, monash university, school of engineering, malaysia. monash university, school of engineering, malaysia, amirkabir university of technology, health technology research institute, department of biomedical engineering- department of biomedical engineering, iran, amirkabir university of technology, department of biomedical engineering, iran, monash university, school of engineering, malaysia, university of wisconsin-madison, department of physics, usa, amirkabir university of technology, department of biomedical engineering, iran
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پست الکترونیکی
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f.prstsh@gmail.com
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Authors
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