massive parallel digital microuidic biochip architecture for automating large-scale biochemistry assays

Micro/nano uidic biochips are used to automate the clinical diagnosis, dna sequencing, drug discovery, and real-time bio-molecular recognition. one of the attractive usages of biochips is lab-on-chip (loc). lab-on-chip technology is a promising replacement for biomedical and chemical apparatus. two main types of micro uidic-based biochips are used: continuous- ow-based and digital micro uidic biochips (dmfb). in dmfbs, liquids, in the form of droplets, are controlled independently and concurrently over a two-dimensional array of cells (or electrodes). digital micro uidic biochips are of high ability to configure and for fault tolerance. in this paper, a new architecture for dmfb with an aim of making a balance between the parameters of exibility, efficiency, cost, and completion time of biological experiments is presented. in the new architecture, a fpga-based structure is used, which increases exibility and parallelizing assay operations. experiments show that the execution times of scheduling, routing, and simulation have improved by about 2.54%, 18.76%, and 12.52%, respectively, with 21% overhead cost in the number of controlling pins.