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a new and efficient method for the synthesis of pyrazolo[3,4-d] pyrimidines catalyzed by iodine
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نویسنده
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matloubi moghaddam firouz ,moafi atiyeh ,khodabakhshi mohammad reza
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منبع
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scientia iranica - 2018 - دوره : 25 - شماره : 6-C - صفحه:3305 -3310
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چکیده
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Substituents of fully new pyrazolo[3,4-d]pyrimidines were synthesized. the synthesis starts with cyanomethylphenylketone that reacts with phenyl hydrazine to produce the corresponding aminopyrazole. the latter undergoes a cyclocondensation with n,n0-bis(arylmethylidene)arylmethane, yielding the final product. both synthetic steps are high yielding (the overall yields between 65-78%). the newly synthesized compounds were characterized by 1h nmr, 13c nmr, and elemental analysis.
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کلیدواژه
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heterocyclic compounds;pyrazolo[3 ,4-d] pyrimidines;iodine-catalyzed reaction;aminopyrazole ,n0-bis(arylmethylidene) arylmethane
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آدرس
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sharif university of technology, laboratory of organic synthesis and natural products, department of chemistry, iran, sharif university of technology, laboratory of organic synthesis and natural products, department of chemistry, iran, sharif university of technology, laboratory of organic synthesis and natural products, department of chemistry, iran
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Authors
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