prognostic role of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the survival of patients with esophageal cancer

Background: different factors can affect the future of a person with cancer. thepatient’s systemic inflammatory response is an important factor. several inflammatorymarkers have been evaluated for measuring the patient’s response to cancer.we evaluated neutrophil to lymphocyte ratio (nlr) and platelet to lymphocyte ratio(plr) as prognostic factors for survival in patients with pathologically proven esophagealcancer.methods: in this retrospective cohort study, patients with pathologically approvedesophageal cancer, who underwent surgical treatment in the cancer institute of iran,were included. demographic, pathological, and laboratory data of patients were obtainedfrom the archive of medical records.results: in this study, 135 patients with esophageal cancer with a mean age of 60were studied. the median time of the follow-up period was 21 months. mean nlrand plr were 7.05 and 898, respectively. patients’ survival had a significant relationshipwith their age, gender, tumor differentiation, receiving chemotherapy, absoluteneutrophil count, total bilirubin, direct bilirubin, and nlr.conclusion: according to the results, in a multivariable investigation, it was demonstratedthat a high nlr has a direct effect on patients’ poor survival.