the effects of digoxin on heart failure mortality and re-admission in a single center cross-sectional study

Introduction: mortality benefit of digoxin prescription in patients suffering from heart failure has been questioned many time. we evaluated these effects among admitted symptomatic heart failure patients. methods: we retrospectively divided our patients into two groups: group a (n=205) were digoxin prescribed, and group b (n=96) were digoxin naïve patients. both groups’ medical records were gathered for one year, and the study endpoints were compared between the two groups. results: the mean age was 62.3±12.1 years and 54.8 % were male. all-cause mortality and readmission occurred in 26.7% and 31.7% of individuals, respectively, without significant differences between the two groups. however, in subgroup analysis, there was a significant relationship between in-hospital mortality and the presence of cardiovascular risk factors. conclusion: digoxin might increase in-hospital mortality in patients with underlying cardiovascular risk factors.