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triglyceride-to-glucose index to detect a non-dipping circadian pattern in newly diagnosed hypertensive patients
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نویسنده
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şaylık faysal ,çınar tufan ,selçuk murat ,akbulut tayyar
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منبع
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journal of cardiovascular and thoracic research - 2022 - دوره : 14 - شماره : 3 - صفحه:147 -152
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چکیده
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Introduction: in this investigation, we aimed to explore the relationship between the triglyceride-glucose (tyg) index and the non-dipping blood pressure (bp) pattern in newly diagnosed hypertensive patients. methods: in this retrospective study, 216 consecutive newly diagnosed hypertensive patients who had undergone 24-hour ambulatory blood pressure (abpm) monitoring and had not received anti-hypertensive drugs were included. non-dipping status was evaluated by a 24-h abpm monitoring in all patients. we categorized the patients into two groups as; dippers (n = 104 cases) and non-dippers (n = 112 cases). the tyg index was derived from the fasting triglyceride and fasting glucose levels using the formula; ln[fasting triglyceride (mg/dl) × fasting glucose (mg/dl)/2]. results: non-dipper group had a higher tyg index than the dipper group. the tyg was an independent predictor of non-dipping bp in hypertensive individuals, according to multivariable analysis. the tyg index was negatively associated with a decrease in both systolic and diastolic bp during the nighttime. the ideal cutoff value of the tyg index in detecting non-dipping status was ≥ 9.01 with 74.1% sensitivity and 71.2% specificity. a roc comparison indicated that the area under the curve value of tyg index was superior to fasting triglyceride, fasting glucose, and homeostasis model assessment of ir (homa-ir) in detecting non-dipping bp. conclusion: the tyg index was an independent predictor of non-dipping status in newly diagnosed hypertensive patients who had undergone 24-hour abpm monitoring and had not received anti-hypertensive drugs. as a simple and easily obtained parameter, the tyg index can be used to detect such pattern among these patients.
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کلیدواژه
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triglyceride-glucose index ,non-dipping hypertension ,insulin resistance ,biomarker ,circadian pattern
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آدرس
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van training and research hospital, department of cardiology, turkey, abdulhamid han training and research hospital, department of cardiology, turkey, abdulhamid han training and research hospital, department of cardiology, turkey, van training and research hospital, department of cardiology, turkey
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پست الکترونیکی
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tayyarakbulut1@hotmail.com
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Authors
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