early results of the resilia inspiris aortic valve in the old age patients - a retrospective comparison with the carpentier edwards magna ease

Introduction: the inspiris resilia aortic valve® (inspiris) is a pericardial bio-prosthesis with a new sterilization procedure that shows promising results in terms of reduced calcification. methods: the 30-day mortality and morbidity were analyzed, comparing the inspiris implanted between may 2017 and the end of january 2019, with its “predecessor”, the carpentier-edwards perimound magna ease (me). echocardiography was performed one-week after surgery. 125 consecutively operated patients were included (59 inspiris, 66 me). results: one patient in the me group died and one patient in the inspiris group had a complicated postoperative course due to right heart failure. two patients (one inspiris, one me patient) suffered a perioperative stroke. the hemodynamic evaluation shows an effective reduction of mean transvalvular pressure gradients after surgery in both groups. inspiris tended to have lower trans-prosthetic pressure gradients (9 mm hg, interquartile range [iqr] 11-7 mm hg versus 12 mm hg, iqr 15-9 mm hg; p = 0.001), reduced trans-prosthetic blood flow acceleration (209 cm/s, iqr 220-190 cm/s versus 227 cm/s, iqr 263-191 cm/s; p = 0.003) and increased permeability indices (57%, iqr 67%- 47% versus 42%, iqr 48%-38%; p8%; p < 0.001). conclusion: there are only few clinical data available from inspiris, and the present analysis confirms good results initial postoperatively with a tendency towards possibly improved hemodynamics compared to me.