Effect of Lavender Cream with or without Foot-bath on Anxiety, Stress and Depression in Pregnancy: a Randomized Placebo-Controlled Trial

Introduction: psychological disorders are associated with maternal and neonatal morbidities. we aimed to evaluate the effect of lavender cream with or without foot-bath on depression, anxiety and stress of pregnant women. methods: in this trial, 141 women at 25 to 28 weeks gestation were randomly assigned into three groups (47 at each group); receiving lavender cream with foot-bath, only lavender cream, or placebo, 2g every night for two months. depression, anxiety and stress were assessed at baseline, and 4th and 8th weeks after intervention, using dass-21. general linear model was used to compare the groups. results: there were three losses to follow-up at the 4th and one more at the 8th week. scores of all three outcomes in both lavender and foot-bath and only lavender groups were significantly lower than those in the placebo group at the 8th week; adjusted difference of depression score -3.3, 95% confidence interval -4.6 to -1.9;-2.4, -3.7 to -1.0, respectively, anxiety score -1.4, -2.6 to -0.2; -1.7,-2.9 to -0.5 and stress score -3.1, -4.7 to -1.5; -2.7, -4.3 to -1.1. at the 4th week, only score of anxiety in the lavender group (-2.3, -3.9 to -0.8) and stress in the both groups (-2.3, -4.1 to -0.5; -1.9, -3.7 to -0.1) were significantly less than those in the placebo group. there were not statistically significant differences between the two experimental groups in terms of the outcomes. conclusion: lavender cream with foot-bath or alone can be used for pregnant women for reducing their stress, anxiety and depression