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gabapentin-based synthesis of novel oxo- and spiro-dihydroquinazoline derivatives
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نویسنده
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khajehali navid ,darehkordi ali
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منبع
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journal of the iranian chemical society - 2020 - دوره : 17 - شماره : 2 - صفحه:433 -440
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چکیده
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New series of gabapentin-based oxo- and spiro-1,4-dihydroquinazolins were synthesized through condensation reaction of isatoic anhydride, gabapentin and aromatic aldehydes or mono/1,3-dicarbonyl compounds. this procedure is environmentally safe due to the presence of water as a solvent. also gabapentin acts as a catalyst via its carboxylic acid functional group. we hope these compounds to be useful for biological activities.
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کلیدواژه
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isotonic anhydride ,gabapentin ,4-dihydroquinazolins ,spiro-1 ,4-dihydroquinazoline
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آدرس
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vali-e-asr university of rafsanjan, department of chemistry, iran, vali-e-asr university of rafsanjan, department of chemistry, iran
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Authors
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