sulfonic acid-functionalized graphitic carbon nitride composite: a novel and reusable catalyst for the one-pot synthesis of polysubstituted pyridine in water under sonication

Graphitic carbon nitride as an interesting sustainable soft nanomaterial has drawn broad interdisciplinary attention because of unique electronic structure and chemical stability. an ultrasound-assisted preparation of a series of polysubstituted pyridines in the presence of a polar and strongly acidic sulfonated magnetic graphitic carbon nitride (fe3o4@g-c3n4-so3h) under milder and faster reaction conditions in water as a green medium was reported. one-pot sequential multicomponent reaction of aromatic aldehydes with acyclic and cyclic ketones, malononitrile and ammonium acetate was afforded the pyridine derivatives in good-to-excellent yields. in view of eco-friendly and economic considerations, this approach offers a straightforward and convenient route to generate biologically active pyridine derivative in an environmentally friendly manner. the fe3o4@g-c3n4-so3h showed high stability and reusability over several reaction sets without noteworthy loss of activity, and thus, this method is a cheap and eco-friendly procedure.