development of deep eutectic solvent extraction method for extraction of zn2+ from powdered milk and baby formula samples and its determination by icp-oes

In the present study, the deep eutectic solvent-based extraction method has been developed for separation of zn prior to icp-oes analysis. five different choline chloride-based deep eutectic solvents were prepared. the zn extraction ability of dess from milk powder and baby formulation samples which contain a high amount of milk protein was investigated. the parameters affecting the extraction efficiency such as the amount and type of solvent, extraction time and ambient temperature were optimized. oxalic acid-based des gave the highest yield and reproducible results and appropriate preparation criteria. it is concluded from the results that des-oxalic can quantitatively extract zn from milky samples. the analytical parameters such as linear calibration range, limit of detection (4.2 µg l−1) and quantification (14.1 µg l−1) were also calculated. the added-found method is successfully applied to erm bd 150 standard reference material, and the recovery values and standard deviation values were found between the ranges of 79.4–97.21 µg l−1 and 4.1–6.31 µg l−1, respectively. the method was also applied to real samples, and the recovery values were found between 73 and 106% in the spiked samples.