a facile and effective procedure for synthesis of polyfunctionalized pyrrolines from simultaneously stirring of carbon disulfide, aniline, arylglyoxals and β-enaminocarbonyls

An efficient one-pot synthesis of 2h-pyrroline derivatives by a four-component reaction between carbon disulfide, aniline, arylglyoxals and β-enaminocarbonyls in acetonitrile at room temperature under mild reaction conditions is reported. the addition reaction has been done to access broad range of 5-hydroxy-4-phenylcarbamodithioate 2-h pyrroline derivatives after about 6 h stirring. all reactions were performed in acetonitrile at room temperature. reactions are clean, and products were isolated by simple filtration.