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a facile zro2 nanoparticles catalyzed synthesis of 2-amino-5-arylpyrimido[4,5-b]quinolinediones
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نویسنده
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mamaghani manouchehr ,jamali moghadam mona ,hossein nia rogheyeh
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منبع
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journal of the iranian chemical society - 2017 - دوره : 14 - شماره : 2 - صفحه:395 -401
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چکیده
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In this investigation, an efficient and ecofriendly multicomponent reaction is described for the green synthesis of 2-amino-5-arylpyrimido[4,5-b]quinolinedione derivatives using zro2 (nps). in this protocol, the reaction of 2,6-diaminopyrimidin-4(1h)-one, arylaldehyde and 1,3-cyclohexanedione or 5,5-dimethyl-1,3-cyclohexanedione in the presence of zro2 (nps) in ethylene glycol at 120 °c produced the desired products in excellent yields (90–98 %) and short reaction times (8–60 min.). use of recyclable catalyst, green solvent, easy workup and excellent yields are the notable features of this method.
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کلیدواژه
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nanocatalyst ,zro2 (nps) ,multicomponent ,pyrimido[4 ,5-b]quinoline ,6-diaminopyrimidin-4(1h)-one
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آدرس
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islamic azad university, rasht branch, faculty of sciences, department of chemistry, iran. university of guilan, faculty of sciences, department of chemistry, iran, islamic azad university, rasht branch, faculty of sciences, department of chemistry, iran, university of guilan, faculty of sciences, department of chemistry, iran
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Authors
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