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sequential one-pot five-component synthesis of tetrazole-based spirotetrahydro-β-carbolines
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نویسنده
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ghandi mehdi ,ahangaran mahdieh mahami ,abbasi alireza
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منبع
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journal of the iranian chemical society - 2017 - دوره : 14 - شماره : 5 - صفحه:1131 -1137
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چکیده
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A one-pot five-component two-step sequential synthesis of tetrazole-based tetrahydrospiro[indene-2,1′-pyrido[3,4-b]indole]-1,3-diones in moderate to good yields is described. the reaction consists of four-component condensation of aromatic aldehydes with tryptamine, trimethylsilyl azide (tmsn3) and isocyanides, followed by addition of ninhydrin. these reactions presumably proceeded through ugi-azide/pictet–spengler processes, respectively.
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کلیدواژه
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tetrazole ,ugi-azide ,pictet–spengler ,spiro[indene-2 ,1′-pyrido[3 ,4-b]indole]-1 ,3-diones
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آدرس
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university of tehran, school of chemistry, college of science, iran, university of tehran, school of chemistry, college of science, iran, university of tehran, school of chemistry, college of science, iran
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Authors
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