fe3o4@ionic liquid-β-cyclodextrin polymer magnetic solid phase extraction coupled with hplc for the separation/analysis of congo red

Fe3o4@ionic liquids β-cyclodextrin polymer(fe3o4@mono-6-deoxy-6-(1-ethyl-imidazolium)-β-cyclodextrin iodide polymer, fe3o4@ils-β-cdcp) was prepared. magnetic solid phase extraction coupled with high-performance liquid chromatography for the separation/analysis of congo red (cr) in water and drysaltery was established. fe3o4@ils-β-cdcp showed a higher adsorption capacity toward cr. cr was adsorbed rapidly by fe3o4@ils-β-cdcp (adsorption efficiency: 95%) and eluted by ethanol (elution efficiency: 96%) at room temperature. under the optimal conditions, preconcentration factor of the proposed method was 20-fold. the linear range, correlation coefficient (r 2), detection limit (dl) and relative standard deviation were found to be 0.005–100.00 µg ml−1, 0.9910, 1.8 g l−1 and 0.61% (n = 3, c = 5.00 µg ml−1), respectively. the adsorption mechanism of cr on fe3o4@ils-β-cdcp was studied through the ftir analysis. the accuracy of the developed method was confirmed by spiking city water, lake water, pond water and drysaltery. fe3o4@ils-β-cdcp can be used repeatedly for 10 times. this proposed method had been successfully applied to the determination of cr in real samples.