nanoammonium salt: a novel and recyclable organocatalyst for one-pot three-component synthesis of 2-amino-3-cyano-4h-pyran derivatives

1,3-propanediaminium methanesulfonate [(pda)(meso3)] was synthesized as the first nanoaliphatic ammonium salt via a safe and simple chemical route in aqueous media. [(pda)(meso3)] ammonium salt was characterized by xrd, tem, sem, eds, dls, afm, 1h nmr, 13c nmr, ft-ir, tg, and elemental analysis. [(pda)(meso3)] ammonium salt was efficiently applied as an eco-friendly and recyclable organocatalyst for the one-pot, three-component synthesis of 2-amino-3-cyano-4h-pyran derivatives. from an economical and environmental point of view, this novel catalyst has the merits of environmental friendliness, high yields, shorter reaction time, simple work-up, easy operation, the avoidance of the organic solvents, and inexpensive catalysts.