a convenient approach for the synthesis of various derivatives of pyrazolo[1,2-b]phthalazinediones in the presence of an efficient supported basic ionic liquid at ambient temperature and solvent-free media

A convenient procedure has been described for one-pot synthesis of various pyrazolo[1,2-b]phthalazinediones at ambient temperature and solvent-free media. first, a novel supported basic ionic liquid ([sipmim]oh@mnps) was prepared and characterized by ft-ir, elemental analysis, vsm, sem, tem and xrd. this catalyst exhibits excellent catalytic activity in one-pot reaction of aromatic aldehydes, phthalhydrazide and malononitrile (or acyclic 1,3-dicarbonyl compounds) to offer cyano-, acetyl- or benzoyl-substituted pyrazolo[1,2-b]phthalazinediones in high yields. moreover, selective synthesis of mono- and bis-pyrazolo[1,2-b]phthalazinediones from dialdehydes was investigated in this approach. the catalyst could be easily separated by an external magnet and reused seven times without any significant loss of activity. an efficient procedure is described for one-pot synthesis of various cyano-, acetyl- or benzoyl-substituted pyrazolo[1,2-b]phthalazinediones in the presence of [sipmim]oh@mnps at ambient temperature and solvent-free media.