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metal-free greener method for the synthesis of densely functionalized pyrroles via a one-pot three-component reaction
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نویسنده
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fatahpour maryam ,hazeri nourallah ,maghsoodlou malek taher ,lashkari mojtaba
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منبع
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journal of the iranian chemical society - 2019 - دوره : 16 - شماره : 1 - صفحه:111 -116
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چکیده
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A convenient and straightforward acid-promoted synthesis of a new series of polyfunctionalized pyrroles has been developed based on a one-pot three-component reaction of acetoacetanilide, benzoin, and ammonium acetate/diverse anilines in acetic acid as a green solvent at 100 °c. the other salient benefits of this transformation include being simple reaction conditions, toxic transition-metal-free, no need of column chromatographic purification, moderate to good yields, eco-friendliness, and readily available starting materials.
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کلیدواژه
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acid-promoted ,polyfunctionalized pyrroles ,one-pot ,green solvent
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آدرس
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university of sistan and baluchestan, faculty of science, department of chemistry, iran, university of sistan and baluchestan, faculty of science, department of chemistry, iran, university of sistan and baluchestan, faculty of science, department of chemistry, iran, velayat university, faculty of science, iran
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Authors
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