2-hydroxyethyl-1-ammonium 3-hydroxypropane-1-sulfonate: a biodegradable and recyclable ionic liquid for the one-pot synthesis of 2-amino-3-cyano-4h-pyrans

2-hydroxyethyl-1-ammonium 3-hydroxypropane-1-sulfonate ‘hahs’ was synthesized as a novel ionic liquid and characterized by various techniques. ‘hahs’ ionic liquid was efficiently applied as a multifunctional promoter for the three-component synthesis of 2-amino-3-cyano-4h-pyrans. the 2-amino-3-cyano-4h-pyrans were produced not only in high to excellent yields but also no toxic solvent or catalyst was used. ‘hahs’ ionic liquid was recovered and reused four times without the considerable decreasing in its activity. the effect of hydroxyl groups in the structure of ‘hahs’ ionic liquid on its catalytic activity was studied. moreover, the biodegradability potential of the ionic liquid was examined using the 5-day biological oxygen demand closed bottle test and the results showed that ‘hahs’ has remarkable biodegradability potential.