investigating the expression levels of bax and bcl-2 genes in peripheral blood lymphocytes of industrial radiation workers in the asaluyeh region

Background: industrial radiography uses gamma or x-ray radionuclide sources to investigate the safety of industrial materials. industrial radiation workers receive the highest occupational radiation doses.objective: the present study investigates the relationship between bax and bcl-2 gene expression variables in industrial radiation workers.material and methods: in this case-control study, data was collected using blood sampling from 40 workers, including two groups of non-radiation and radiation workers employed at the location. expression levels of bax and bcl-2 genes were assessed in the laboratory. the environmental and absorbed doses of workers were measured using environmental and pen dosimeters.results: statistical analysis showed that the radiation group’s bcl-2 gene expression level was significantly higher. findings also demonstrated a correlation between bcl-2 gene expression and the number of workdays. also, the bax gene expression did not show a significant change, and the expression ratio of bax/bcl-2 was insignificant in the two groups. conclusion: exposure to low doses of radiation could promote an adaptive response in cells by increasing bcl-2 gene expression.