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Synthesis of some Novel Metal Complexes of 4-Hydroxy Benzopyran-2-0nes as Antimicrobial Agent
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نویسنده
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Vyas K.B. ,Nimavat K.S. ,Jani G.R. ,Hathi M.V
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منبع
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journal of sciences islamic republic of iran - 2009 - دوره : 20 - شماره : 2 - صفحه:111 -114
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چکیده
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Complexes of 3-[ {3-(3'-bromo phenyl) }-prop-2-enoyl]-4-hydroxy-6-methyl2h- chromen-2-one with cu(ii), ni(ii), fe(ii), co(ii) and mn(ii) have been synthesized and characterized using elemental analysis, ir spectra and conductivity measurements. these studies revealed that they are having octahedral geometry of the type [ml2 (h2o)2]. in-vitro antimicrobial activity of all synthesized compounds and standard drugs have been evaluated against four strains of bacterial culture and one fungus, which includes two gram +ve bacterialculture and two gram -ve bacterial culture, which show net enhancement in activity on co-ordination of metals with ligand but moderate activity as compare to standard drugs.
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کلیدواژه
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Antimicrobial activity; Coumarin; Metal complexes; Structural study
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آدرس
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Government Science College, Department of Chemistry, India, Government Science College, Department of Chemistry, India, M.N. College, Department of Chemistry, India, R.R. Mehta Science College, India
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پست الکترونیکی
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kirankartik@yahoo.com
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Authors
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