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An Efficient, Three-Component Synthesis of 3,4-Di Hydropyrimidin-2(1H)-Ones Using LaCl3/ClCH2COOH as Environmentally Benign and Green Catalytic System
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نویسنده
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Khajesamani H. ,Pouramiri B. ,Tavakolinejad Kermany E. ,Khabazzadeh H.
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منبع
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journal of sciences islamic republic of iran - 2014 - دوره : 25 - شماره : 4 - صفحه:323 -27
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چکیده
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An improved, simple, and facile synthesis of 3,4-dihydropyrimidin-2(1h)-ones by employing three-component, one-pot condensation reaction of b-keto ester, aromatic aldehydes, and urea or n-methylurea using lacl3/clch2cooh as an inexpensive and green chemistry catalyst system under solvent-free conditions described. compared with the classicalbiginelli reaction conditions, this method has the advantages of good to excellent yields (80-99%) and short reaction time.
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کلیدواژه
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One-pot condensation ,Solvent –free ,Lanthanum(III)chloride ,Dihydropyrimidinones
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آدرس
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shahid bahonar university of kerman, ایران, shahid bahonar university of kerman, ایران, shahid bahonar university of kerman, ایران, shahid bahonar university of kerman, ایران
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Authors
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