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Synthesis and Antimicrobial Activity of Some 2[(4-Substituted-Phenyl-3-Chloro-Azetidin-2One)-5-(2-Methylamino-4-Phenyl-l,3-Thiazolyl-]-l, 3,4-Thiadiazoles
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نویسنده
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Sonwane S.K. ,Srivastava S.D. ,Srivastava S.K.
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منبع
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journal of sciences islamic republic of iran - 2009 - دوره : 20 - شماره : 3 - صفحه:227 -232
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چکیده
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A new 2-[(4-substituted-phenyl-3-chloroazetidin-2-one)-5-(2'-methylamino 4-phenyl-1', 3'-thiazolyl-]-1, 3, 4-thiadiazoles, 5(a-n) were synthesized from 2-substituted-benzylideneamino-5-[2'-methylamino-4'-phenyl-1',3'-thiazolyl]-1,3, 4-thiadiazole, 4(a-n) using 2-amino-4phenyl-1, 3-thiazole as a starting material. thesynthesised compounds have been screened in vitro for their antimicrobial activityagainst bacillus subtilis, escherichia coli. klebsiella pneumoniae andstreptococcus aureus bacteria and aspergillus niger, aspergillus flavus, fusariumoxisporium and trichoderma viride fungi respectively. some of the compoundsdisplayed pronounced biological activity.
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کلیدواژه
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2-Amino-4-phenyl-1 ,3-thiazole; Thiadiazole; Arylidene; 2-Azetidinone; Antimicrobialactivity
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آدرس
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Dr. H.S. Gour Central University, Synthetic Organic Chemistry Laboratory, Department of Chemistry, India, Dr. H.S. Gour Central University, Synthetic Organic Chemistry Laboratory, Department of Chemistry, India, Dr. H.S. Gour Central University, Department of Chemistry, Synthetic Organic Chemistry Laboratory, India
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پست الکترونیکی
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sonwane_chem@yahoo.com
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Authors
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