Pattern and sensitivity of microorganisms causing urinary tract infection at teaching hospital

Objective: to determine the pattern and sensitivity of pathogens causing urinary tract infection at tertiary care hospital. methods: using clean catch method,urinary samples were collected from patients admitted in urology ward,liaquat university hospital jamshoro from 1 st january 2011 to 31 st december 2011 who had suspected urinary tract infection. samples sent to diagnostic and research laboratory at pathology department,liaquat university of medical and health sciences,jamshoro. all samples were tested by international standard method under supervision of qualified microbiologist. antibiotic sensitivity of isolated micro-organisms was tested for commonly used antibiotics by kirby baur technique. results: out of admitted patients total of 458 samples were sent during study period. significant bacteriuria was found in 335 (73.14%) samples,insignificant bacteriuria in 23 (5.02%) samples,while 100 (21.8%) samples were sterile. the most common pathogens isolated were e.coli in 297 (64.41%) samples,klebseilla spp and enterobacter each in 51 (11.31%) samples,proteus in 36 (7.8%) samples,pseudomonas in 15 (3.27%) samples and citrobacter in 8 (1.74%) samples. conclusion: seventy three percent of samples showed significant growth. high yield of positive cultures showed good clinical co-relation in suspected cases of uti. organisms isolated in urine cultures were gram negative rods. study proves that pathogens causing urinary tract infections are developing resistance against commonly used antibiotics.