Frequency of H. Pylori Infection in Patients Undergoing Upper Gastrointestinal Endoscopy At Tertiary Care Unit

Object: to find out the frequency of h.pylori infection in patients undergoing upper gi endo-scopy. materials and methods: this study was conducted at surgical unit-i liaquat university hospital and private hospital located at hyderabad sindh from june 2010 to july 2011. after taking written consent those patients were enrolled who fulfilled the inclusion criteria. study was approved by ethical committee. presence of h.pylori infection was confirmed by histopathological examination of samples taken during upper gastrointestinal endoscopy. presence or absence of gastritis was also observed. gif 140 olympus gastro-video-scope was used for the procedure. results: 165 patients were enrolled in the study,among them 82 were males and 83 females with mean age 41.04 ±15.9 and 35.9 ±11.5 years respectively,among males 43(52.43%) were positive and 39(47.5%) were negative for h.pylori infection,while in females 38(45.78%) were positive and 45(54.2%) negative for the same. when compared for gender differences there was slightly higher prevalence in males. antral gastritis was common association with h.pylori infection in both genders with higher prevalence in males as compared to females. 5 patients (5%) were found to have gastric carcinoma without any h.pylori association. conclusion: helicobacter pylori infection is quite frequently found in association with gastritis in males as well as females with slightly higher prevalence in male.