effects of tarragon powder on glucose metabolic changes, lipid profile and antioxidant enzyme levels in type 2 patients with diabetes: a randomized, double-blind, placebo-controlled, clinical trial

Background: the antioxidant and anti-inflammatory properties of tarragon make it known as an antidiabetic plant. diabetes mellitus, an endocrine, metabolic disease, is a leading global health emergency and associated with serious complications. objectives: this study aimed to assess the effects of tarragon powder supplementation on glucose metabolism, lipid profile, and antioxidant status in the diabetic population. methods: patient screening and selection for this clinical trial lasted one month. tarragon supplement consumption by patients lasted 2 months (8 weeks); meanwhile, they were followed up. sixty male and female patients with type 2 diabetes were randomly assigned to the tarragon receiver group (n = 30) and placebo receiver group (n = 30). the intervention group received a tarragon capsule (500 mg) 3 times a day, and the control group received placebo capsules. fasting blood glucose (fbg), two-hour postprandial glucose (2-hpp), glycated hemoglobin (hba1c), insulin, lipid, and antioxidant profile were evaluated at the start and the end of the research. results: in the tarragon receiver group, fbg, 2-hpp, hba1c%, insulin resistance, lipid, and antioxidant profile significantly improved, compared to the placebo group, after adjuvant therapy with tarragon (p < 0.05). conclusions: supplementation with tarragon powder in type ii patients with diabetes for 2 months exerts a beneficial effect on improving the glycemic profile, lipid profile, and antioxidant status.