The results of treatment with radioactive iodine and surgery in patients with toxic multi nodular goiter (tmng) from 1999 to 2005 in Ahvaz

Background: the aim of this study was the evaluation of theresult of two treatment methods (radioactive iodine and surgery),recurrence rate and hypothyroidism after treatment and side effectsin toxic multi nodular goitermaterial and methods: in this retrospective study 354 cases oftoxic multi nodular toxic goiter patients that referred to endocrineclinic and treated with one of the above-mentioned treatmentmethod were evaluated. demographic data, thyroid examination,recurrence of hyperthyroidism, incidence of hypothyroidism aftertreatment and side effects of treatment were collected.results: from 326 cases, 20% were male and 80% were female.mean age was 48?14. from 326 patients treated with radioactiveiodine, only 34 cases (10%) relapsed after treatment and 186patients (57%) showed hypothyroidism after treatment.from 28patients underwent surgery, only 2 patients (7%) had recurrence ofhyperthyroidism, but hypothyroidism after surgery was seen in halfof patients and in 10 patients (36%) long-term surgicalcomplications such as laryngeal nerve damage andhyporparathyroidism were seen. euthyroid cases withoutpermanent side effects had not significant difference in these twotreatment methods (33% in surgery versus 29% in radioactiveiodine (p > 0.05).conclusion: surgery in patients with tmng does not have anyadvantage on radioactive iodine. surgery can lead to lifelongcomplications in patient.