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role of non-coding rna as a biomarker of response to therapeutic agents in colorectal cancer
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نویسنده
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mahmoudi roghayeh ,salem elham ,khadempar saedeh ,rastgoo haghi alireza ,keshtpour amlashi zahra ,saki sahar ,darvishi talemi masoumeh ,afshar saeid
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منبع
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jentashapir journal of cellular and molecular biology - 2022 - دوره : 13 - شماره : 1 - صفحه:1 -7
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چکیده
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Chemoresistance is a severe drawback to the successful and effective treatment of colorectal cancer (crc). comprehensive molecular mechanisms of chemoresistance facilitate the development of effective therapeutic strategies to overcome chemoresistance in crc. the dysregulation of several non-coding rnas was related to chemoresistance in crc.considering the importance of lncrnas and mirnas as prognostic and response to treatment biomarkers, this review focuses on the role of mirnas and lncrnas in crc chemoresistance. non-coding rnas have an essential role in tumor progression, metastasis, and crc chemoresistance. thus, mirnas and lncrnas can be used to respond to therapeutic biomarkers in crc.
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کلیدواژه
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colorectal neoplasm ,chemoresistance ,lncrna ,mirna
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آدرس
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hamadan university of medical sciences, research center for molecular medicine, iran, hamadan university of medical sciences, research center for molecular medicine, iran, shahid sadoughi university of medical sciences, departemant of medical genetics, iran, hamadan university of medical sciences, department of pathology, iran, hamadan university of medical sciences, departemant of radiotherapy, iran, hamadan university of medical sciences, iran, bu-ali sina university, faculty of science, department of biology, iran, hamadan university of medical sciences, research center for molecular medicine, iran
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پست الکترونیکی
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safshar.h@gmail.com
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Authors
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