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   Comparison of Effect of Aloe vera Gel and Nystatin on Candida Species: An in Vitro Study  
   
نویسنده rezvaninejad rayehehossadat ,rezvaninejad raziyehsadat ,ashoorian mohammad javad ,talebi maryam
منبع jundishapur journal of health sciences - 2022 - دوره : 14 - شماره : 3 - صفحه:1 -5
چکیده    Background: oral candidiasis is an opportunistic fungal infection that leads to acute and chronic infections in the mouth and gastrointestinal tract. according to studies,commonantifungal drugs have some side effects and sometimes fail in candida albicans candidiasis infections. objectives: this study aimed to compare the efficacy of aloe vera to that of nystatin on oral candida species in vitro. methods: this laboratory study was prepared in vitro from a collection of fungi and bacteria in iran. the measured inhibitory concentration was within the range of 1:1 to 1:2048. the data were analyzed using spss software (version 24). results: in c. albicans species, the inhibitory concentration of aloe vera gel was 312.5 l/ml. the inhibitory concentrations for candida glabrata and candida tropicalis were 1250 and 625l/ml, respectively. in all groups, there was a significant relationship between aloe vera and nystatin. conclusions: aloe vera gel showed antifungal properties in all tested species. the inhibitory concentrations of aloe vera were much higher than nystatin. therefore, to use this plant for humans, the concentration of its toxicity to humans should be estimated beforehand to avoid possible harm.
کلیدواژه Aloe Vera ,Nystatin ,Inhibitory Concentration ,Candida
آدرس mcgill university, faculty of dentistry, Canada, kerman university of medical sciences, school of dentistry, department of oral medicine, Iran, hormozgan university of medical sciences, student research committee, faculty of dentistry, Iran, hormozgan university of medical sciences, student research committee, faculty of dentistry, Iran
 
     
   
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