Association between dietary salt intake and reservation of renal function in patients with mild hypertension

Background: it is now hypothesized whether restricted salt intake can be a potentialprecursor to renal dysfunction in mild hypertension state. we aimed to study the associationbetween salt intake and renal function in patients with mild hypertension.methods: one hundred consecutive hypertensive iranian patients (with systolic blood pressure140-160 mmhg and/or diastolic 90-100 mmhg) who were referred to the hypertension researchcenter, isfahan, iran, between 2011 and 2014 for screening of hypertension were assessed. renalfunction was assessed by measuring serum creatinine (cr) and creatinine clearance (crcl). dailysalt intake was assessed on the basis of 24 h urinary sodium excretion.results: there was no association between the amounts of sodium intake and serum crconcentration (r = 0.138, p = 0.174), however, an association was revealed between sodiumintake and value of crcl (r = 0.303, p = 0.003). multivariable linear regression model showedthat sodium intake could effectively predict renal function assessed by crcl (beta = 0.070,p = 0.016).conclusion: there is an association between sodium intake and reservation of renal functionin mild hypertension state and thus by restriction of dietary salt intake, reserving renal function,and preventing appearance and progression of renal insufficiency in higher degrees ofhypertension can be facilitated.