coronary artery bypass grafting in advance aged patients

Introduction: this study aimed to assess the impact of coronary artery bypass grafting (cabg) on outcomes in elderly patients compared to younger patients. method: an observational case-control study was conducted involving 535 patients, divided into two groups: older adults (≥75 years) and younger adults (<75 years). all patients underwent cabg following a similar protocol. the primary endpoints focused on early post-procedure outcomes, including in-hospital mortality and the duration of icu or hospital stay. patients were followed up for six months, and secondary study endpoints included long-term mortality, left ventricular ejection fraction, re-hospitalization rates, and repeated revascularization. results: 535 patients who underwent cabg were enrolled in this study. the smoking habit was significantly higher among younger adults (38.2% vs. 12.5%, p=0.001). hypertension was more prevalent among older adults than younger adults (75% vs. 60%, p=0.044). ldl cholesterol serum levels were higher among younger adult patients (94.9 ±32.5 vs. 80.9 ±32.9, p=0.028). in-hospital death was not significantly different between younger and older adults (2.8% vs. 5.0%, p=0.34). mortality in the six-month follow-up was non-significantly higher in the elderly (2.1% vs. 8.1%, p=0.06).a significant proportion of patients in both groups (46.9% in younger patients vs. 40% in older ones, p=0.40) received dual antiplatelet therapy (dapt) prior to cabg due to a recent myocardial infarction and receipt of a new stent, but without increased major bleeding in both groups.conclusion: cabg should be considered a viable treatment option for elderly patients with acceptable operative risk in current clinical practice.