evaluating value of positive t wave in lead v1 and tv1 >tv6 pattern in predicting significant coronary artery disease in patients undergoing coronary angiography

Background: the aim of this study was to predict significant coronary artery disease (cad) in patients undergoing coronary angiography.methods: in this cross-sectional study, data of 384 patients who underwent angiography during 2015-2017 were reviewed. electrocardiograms (ecgs) were evaluated in terms of having positive t wave in lead v1 (tv1) described as t wave with amplitude of more than 0.15 mv and angiography records were assessed for presence of significant cad defined as presence of ≥ 70% internal diameter stenosis in at least one major epicardial coronary artery or more than 50% stenosis in left main artery (lma).results: out of 384 patients who participated in this study with mean age of 63.6 ± 10.2 years (40-89 years), 71.6% showed positive tv1 and significant cad simultaneously and left anterior descending artery (lad) and left circumflex artery (lcx) lesions were more frequently reported in coronary angiography. based on chi-square test, the prevalence of significant cad was obviously more in those with positive tv1 as compared to those without this finding [odds ratio (or) = 2.74, 95% confidence interval (ci): 1.80-4.19, p < 0.001]. mann-whitney test showed significant difference in number of coronary arteries involved in cad between presence of positive and negative t wave in lead v1 (p < 0.001). great number of patients with significant cad had remarkably higher t wave amplitude in lead v1 in comparison to lead v6 (or = 6.22, 95% ci: 3.14-12.30, p < 0.001).conclusion: positive tv1 and tv1 > tv6 pattern can be considered as a predictor forsignificant cad in patients with otherwise normal ecg.